Protect Yourself with the Typhoid Vaccine in Singapore

Typhoid fever is a serious bacterial infection caused by Salmonella typhi, typically spread through contaminated food or water. Symptoms may include high fever, stomach pain, rash, muscle aches, cough, and fatigue. Without treatment, the illness can lead to serious complications.
While the risk of contracting typhoid within Singapore is very low thanks to the country’s standards of sanitation and hygiene, travellers visiting certain regions where typhoid is more common — such as parts of South Asia, Africa, and South America — may be at increased risk. For these individuals, vaccination is recommended as a preventive measure.
Whether you're planning a family holiday or business trip, this guide provides essential information about the typhoid vaccine you may need before travelling, including availability, scheduling, and who should consider it.
What Is the Typhoid Vaccine?
The typhoid vaccine helps protect against typhoid fever. In Singapore, two types of typhoid vaccines are available:
- Typhim Vi An injectable vaccine that provides protection for approximately 2 to 3 years.
- Ty21a (Vivotif) An oral vaccine given as a course of four capsules taken every other day, offering protection for up to 5 years.
These vaccines work by stimulating the immune system to produce antibodies against Salmonella typhi, thereby reducing the risk of infection. The choice between these vaccines depends on factors such as age, travel destination, duration of stay, and personal preference. Your healthcare provider can help determine which vaccine is most suitable for your specific needs.
Who Should Get the Typhoid Vaccine?
The typhoid vaccine is generally recommended for:
- Travellers Individuals planning to visit regions where typhoid fever is endemic, including parts of South Asia, Africa, Latin America, and Southeast Asia.
- Individuals at increased risk Such as those in close contact with confirmed carriers of Salmonella typhi or working in environments with potential exposure.
Vaccination is generally not required for residents of Singapore, as the country maintains high standards of sanitation and hygiene that significantly reduce the risk of typhoid infection.
When and How Often Should You Get Vaccinated?
- Typhim VI (Injectable): A single dose is administered via injection. A booster is recommended every 3 years if the risk of exposure persists.
- Ty21a (Vivotif - Oral) Four doses are taken every other day, with the final dose completed at least one week before travel. A booster is recommended every 5 years.
It's advisable to receive the vaccine at least 2 weeks before travelling to allow time for immunity to develop.
What to Expect During and After the Vaccination
The typhoid vaccine is administered either as an injection (Typhim Vi) or orally as capsules (Ty21a/Vivotif), depending on the type selected. Your healthcare provider will explain the process during your appointment and help you choose the most suitable option.
Common side effects may include:
- Pain, redness, or swelling at the injection site (for injectable vaccines)
- Nausea or mild abdominal discomfort (for oral vaccines)
- Headache or fatigue
Severe allergic reactions are rare, but immediate medical attention is required if you experience symptoms such as difficulty breathing, swelling of the face or throat, or hives. It’s important to inform your healthcare provider of any known allergies or prior adverse reactions to vaccines before receiving the typhoid vaccine.
Book Your Typhoid Vaccine in Singapore

Getting protected against typhoid fever is simple and accessible in Singapore. At Healthway Medical, our clinics provide convenient access to experienced doctors who will review your travel plans and medical history to help determine if the typhoid vaccine is right for you.
With professional guidance and friendly support throughout the process, you can feel confident and prepared for your journey abroad.
Contact your nearest Healthway Medical clinic today to book a consultation and take a smart step toward protecting your health while travelling.
Book Your Vaccination